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Saturday 20 June 2015

Oxygen Benefits: Learn healing hidden wounds of cancer

Most cancer patients undergo radiation as it becomes necessary part of live-saving treatment. But some patients experience certain side effects with radiation. These cases were considered by certain doctors who took an unusual approach for healing the hidden wounds of cancer.

For many years, researchers have been looking for way to use oxygen for fighting cancer. Latest study shows that mice’s that were given high-dose of oxygen helped the efforts for stimulating the immunity system against tumors. The director of Clinical Research and Immunology for the American Cancer Society, Susanna Greer was exited with this work and termed it a simple approach for making the cancer therapies work better.

Oxygen helps healing hidden wounds of cancer: CASE I
Oxygen benefits the cancer patients by healing the hidden wounds of cancer. The case below describes how a patient who underwent cancer treatment took the oxygen benefits for healing the hidden wounds of cancer.

Shelly Mayberry, a 40-year old cancer patient had anal cancer for which she underwent both chemo and intense radiation therapy. This cured her cancer but she was left with open sores that didn’t heal properly. Her doctor told that radiation can cause wounds on both inside and outside the body. These wounds of cancer can also be very long-term.

She was asked to get inside a special hyperbaric chamber where she was asked to breathe pure oxygen for a two-hour long session. The intake of pure oxygen helps promote the growth of new blood vessels. Now the radiation damaged tissues were actually having more blood and hence were getting higher oxygen delivery. This helped for faster healing; Shelly was able to hop back to her husband Harley after six weeks of the oxygen sessions.

Oxygen helps healing hidden wounds of cancer: CASE II
Another patient named Enio Monsanto; 82 years old received a hyperbaric oxygen therapy (HBOT) after he was diagnosed with a squamos cell skin cancer on left shin area above his ankle. He was informed that the cancer was not life threatening, but it would continue to grow in size. He had to undergo radiation for treating his condition as he was told by the doctor that this cancer cannot be operated on.

The radiation treatment killed the cancer lesion but the area was left as if a nasty burned wound. This wound didn’t respond well to the conventional wound treatment instead it began growing quickly in size. Then the doctors informed him the only way to treat this burn wound was by undergoing a skin graft. They also informed that this procedure has only about 50% success rate.

His family researched and found about hyperbaric oxygen therapy and convinced by its success rate decided to opt for it for treating his wounds. The hyperbaric oxygen therapy is known to successfully treat the wounds from radiation for cancer treatment. After undergoing this therapy, Enio’s leg has been healed from the damage caused by radiation therapy.

Benefits of oxygen for Healing Wounds of Cancer: It helps to delay the radiation injuries, thermal burns, soft tissue infections and flaps and skin grafts.

Most researchers feel that oxygen therapy is beneficial for AIDS patients. However, even after considering all the benefits of oxygen therapy, it has not been found to destroy the HIV virus. Some of the study shows that the oxygen therapy helps to provide relief in AIDS related cancer patients.


References:

®    “Doctors say oxygen can heal cancers hidden wounds” by Maureen McFadden dated 4th June, 2015.
®     Dole, M., Wilson, F.R. & Fife, W.P. (1975). Hyperbaric Hydrogen Therapy: A Possible Treatment for Cancer. Science, 190, 152-154.
®    DeVita, M.A., Friedman, Y. & Petrella, V. (1993). Mask Continuous Positive Airway Pressure in AIDS. Critical Care Clinics, 9, 137-151.
®   Teicher, B.A. & Rose, C.M. (1984). Oxygen-Carrying Perfluorochemical Emulsion as an Adjuvant to Radiation Therapyin Mice. Cancer Research, 44, 4285-4288.
®  Kranke P, Bennett M, Roeckl-Wiedmann I, Debus S (2004). Kranke, Peter, ed. "Hyperbaric oxygen therapy for chronic wounds". The Cochrane Database of Systematic Reviews (2): CD004123.
®Undersea and Hyperbaric Medical Society. "Hyperbaric Oxygen Treatments for Complications of radiation Therapy". Retrieved 2011-08-21.
®Undersea and Hyperbaric Medical Society. "Skin Grafts and Flaps Compromised". Retrieved 2011-08-21.
®Undersea and Hyperbaric Medical Society. "Thermal Burns". Retrieved 2011-08-21.
®Bennett MH, Feldmeier J, Hampson N, Smee R, Milross C (2012). "Hyperbaric oxygen therapy for late radiation tissue injury". The Cochrane Database of Systematic Reviews 5 (5): CD005005.
®www.oxyhealth.com. "Portable Hyperbaric Chambers | Hyperbaric Oxygen Chamber | Hyperbaric Oxygen". Oxyhealth.com. Retrieved 2010-09-25.

Saturday 13 June 2015

Acute Lymphoblastic Leukemia, Childhood - Treatment Overview

Acute Lymphoblastic Leukemia, Childhood Topic-overview
Acute lymphoblastic leukemia is a common form of cancer in children. Acute lymphoblastic leukemia (ALL) occurs five times more commonly in children. The survival rates of the ALL have drastically improved since 1980s and the current survival rates is greater than 85%. The improvement in the survival rates is due to treatment of a large number of children on the sequential standardized research protocols. It is estimated that about 75 to 85 percent of children who are diagnosed with ALL participated in the trials. The goal of these trials was to achieve an improvement in the clinical outcomes and minimize the late-occurring adverse effects.

Acute Lymphoblastic Leukemia, Childhood Cause
The actual cause of ALL is still unknown. Research is still going on all the time to uncover all the possible causes of ALL in children. It has been observed that children with certain genetic disorders like Down’s syndrome are at higher risk for developing ALL. Also sisters or brothers of a child with ALL (Specifically in case of identical twins) have slightly greater risk for developing ALL themselves. However, this risk is quite small compared to children having genetic disorder. Unlike all cancers, ALL in children is not infectious and hence it cannot be passed on from one person to another.

Symptoms of Acute Lymphoblastic Leukemia, Childhood
The production of the normal blood cells gets reduced due to the multiplication of the leukemia cells in the bone marrow. Lack of the red blood cells caused by anemia makes children feel lethargic and tired. Children starts to develop bruises and the bleeding may take longer to stop. This is caused from low number of platelets present in their blood cells which are known to help clotting of the blood. Sometimes, children may suffer from certain infections due to the low number of normal white blood cells.

A child will likely feel unwell and may complain of pains and ache sin the limbs. Your children may also have swollen lymph glands.
In the early stages of ALL some of the commonly found symptoms are:

Easily feeling tired and weak
Fever
Bruises
Enlarged lymph nodes due to overproduction of immature lymphocytes
Pain in joints or bones

Initially, the symptoms are similar to viral infection but when they sustain for more than a week or two then it clarifies the diagnosis.

Diagnosis:
Your doctor will evaluate your child and their symptoms and doing tests. When a child shows symptoms that could be possibly caused by cancer then they will be referred by their GP to either of the following specialists:

A pediatric oncologist who is specialized for treating children suffering from cancer.
A pediatrician who is a specialists for treating children
A pediatric hematologist who is specialized for treating blood disorders
Most children diagnosed with cancer will undergo treatment in a Principal Treatment Center within a hospital.
Tests:
Your doctor will perform physical exam of your child to reveal swollen liver, spleen and lymph nodes, bruising and any signs of bleeding. Your child will be asked for blood tests so as to verify your platelet count, complete blood count or CBC including the WBC (white blood cell) count, lumbar puncture or the spinal tab for checking the leukemia cells in the spinal fluid.

Tests will be performed to look for any changes in the DNA inside your abnormal white cells. Certain changes in DNA help to determine what kind of treatment is recommended for your children.

Treatment:
The initial goal of your treatment is to get back your blood count to normal. If this occurs then the bone marrow looks healthy under the microscope and cancer will be in complete remission.

Chemotherapy is the first treatment tried to achieve complete remission. After achieving initial complete remission, more treatment is required for curing this condition. The further treatment might include radiation to the brain or more chemotherapy. The bone marrow transplant or the stem cell from another person can be done. The further treatment depends on age and health of your child, genetic changes in the leukemia cells, availability of donor for stem cell transplant and the number of chemotherapy courses your child has undergone.

Acute Lymphoblastic Leukemia, Childhood Prevention
Acute lymphoblastic leukemia in children can be prevented by avoiding contact with chemicals, radiation and certain toxins.

Acute Lymphoblastic Leukemia, Childhood Support & Resources
Most children who are diagnosed with ALL are cured and most of them grow and develop normally. If you have any specific concerns regarding your child’s condition and the types of treatment to be given then you should talk with your doctor.

Being a parent of a child having cancer is worst situation. But you should panic instead you can check out India Cancer Surgery Site which will suggest you best treatment at affordable prices. India has been a favorite medical tourism place in recent years with the availability of experienced and highly skilled doctors. The team of doctors and nurses help support your child and family while you visit for medical treatment. It is advised to discuss any difficulties you may have with your treatment team before your visit to India.
References:

®   Sulong S, Moorman AV, Irving JA, Strefford JC, Konn ZJ, Case MC, Minto L, Barber KE, Parker H, Wright SL, Stewart AR, Bailey S, Bown NP, Hall AG, Harrison CJ (Jan 1, 2009). "A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups.". Blood 113 (1): 100–107.